Erythromycin 2% Topical Solution is an anti acne vulgaris solution with bacteriostatic action against propionibacterium acnes.

Packaging: 60ml PE Bottle with applicator

Erythromycin 2 w/w.

 

3. PHARMACEUTICAL FORM

 

Solution for topical use.

 

4. CLINICAL PARTICULARS

 

 

 

4.1 Therapeutic indications

 

Stiemycin is indicated for use in the treatment of acne vulgaris.

 

4.2 Posology and method of administration

 

To be applied to the affected area twice daily after washing with soap and water.

 

4.3 Contraindications

 

Stiemycin is contraindicated in patients with known sensitivity to any of the ingredients.

 

4.4 Special warnings and precautions for use

 

Avoid contact with eyes and other mucous membranes. Concomitant topical acne therapy should be used with caution because a cumulative irritant effect may occur.

 

4.5 Interaction with other medicinal products and other forms of interaction

 

None known.

 

4.6 Pregnancy and lactation

 

There is no evidence of hazard from erythromycin in human pregnancy. It has been in wide use for many years without apparent ill consequence.

 

4.7 Effects on ability to drive and use machines

 

None.

 

4.8 Undesirable effects

 

None.

 

4.9 Overdose

 

Not applicable.

 

5. PHARMACOLOGICAL PROPERTIES

 

 

 

5.1 Pharmacodynamic properties

 

Erythromycin suppresses Propionibacterium acnes, a resident bacterial of sebaceous follicles, and as a result of this organism's role in the hydrolysis of triglycerides to free fatty acids, administration decreases fatty acid formation. This is thought to be responsible for its effectiveness in reducing acne lesion counts and the fatty acid to fatty ester ratios in acne patients.

 

5.2 Pharmacokinetic properties

 

Not applicable.